- Anatomy of The Spine
- Back Pain in Children
- Caring for your Spine
- Emerging Spinecare Trends
- Evaluation of Spinal Disorders
- Exercise and The Spine
- Intervention - Spinal Disorders
- Intervertebral Disc
- Non Surgical Options
- Nutrition and Spinecare
- Options for Spine Treatments
- Pregnancy and Back Pain
- Prevalence of Spine Disorders
- Sleep and the Spine
- Spinecare Introduction
- Spinehealth and Disease
- Surgical Interventions
- Treatment with Medications
- Understanding Back Pain
Spinecare Topics
Spinehealth and Disease
The Healing Spine
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The Healing Spine
Secondary mechanisms of spinal cord compromise result from the numerous chemical and structural mechanisms that follow SCI; the formation of oxidative free radicals, calcium-mediated damage, the release of proteases and cytokines, cytoskeletal dysfunction, excitotoxicity, immune reactions, apoptosis, and necrosis all come into play following spinal cord injury. These sources of secondary damage interact in complex ways that scientists are just beginning to understand. Identification of each of these mechanisms brings researchers a step closer to controlling or intervening in each process.
Novel approaches in treatment include surgical grafting of peripheral nerve pieces and fetal tissue into the damaged spinal cord, administering growth factors, genetically manipulating cell death programs, and neutralizing or bypassing natural growth-inhibiting substances and preventing astrocyte proliferation after SCI. Combined therapies such as stem cells and near infrared laser in the 810nm wavelength have shown promise in producing meaningful functional recovery following SCI in animal studies. Combinations of such therapies have produced the first evidence that some functional regeneration of a completely severed spinal cord is possible.
Basic neuroresearch has led to a better understanding of the presence and role of trophic factors, growth barriers in the CNS, and the intrinsic capacity of nerve cells to grow. The exciting results of strategies that combine these interventions suggest that such approaches will ultimately prove the most successful for regenerating spinal cord pathways in humans.
Novel approaches in treatment include surgical grafting of peripheral nerve pieces and fetal tissue into the damaged spinal cord, administering growth factors, genetically manipulating cell death programs, and neutralizing or bypassing natural growth-inhibiting substances and preventing astrocyte proliferation after SCI. Combined therapies such as stem cells and near infrared laser in the 810nm wavelength have shown promise in producing meaningful functional recovery following SCI in animal studies. Combinations of such therapies have produced the first evidence that some functional regeneration of a completely severed spinal cord is possible.
Basic neuroresearch has led to a better understanding of the presence and role of trophic factors, growth barriers in the CNS, and the intrinsic capacity of nerve cells to grow. The exciting results of strategies that combine these interventions suggest that such approaches will ultimately prove the most successful for regenerating spinal cord pathways in humans.
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